199 ingredients in the Skinlumis database. Every mechanism. Every interaction. Decoded against real outcome data from the network.
Prescription-strength retinoid with the most robust clinical evidence base for photoaging, acne, and dyschromia. The molecule against which all other retinoids are benchmarked.
A multitasking B3 derivative that strengthens the skin barrier, regulates sebum, brightens uneven pigmentation, and reduces redness. Among the best-tolerated actives in dermatology.
The most potent and best-studied form of topical Vitamin C. A pure, water-soluble antioxidant that neutralises free radicals, brightens, and is a co-factor for dermal collagen synthesis.
A naturally occurring dicarboxylic acid found in cereal grains. Multi-functional: anti-inflammatory, anti-bacterial, and tyrosinase-inhibiting. One of the few actives safe for pregnancy and rosacea.
The most abundant ceramide in the human stratum corneum; restores the lipid lamellae that hold barrier cells together.
The broadest-spectrum mineral filter, protects from UVA1 through UVB. Sits on the skin and reflects/absorbs UV.
Originally used systemically to control bleeding, topical tranexamic acid has emerged as a star ingredient for stubborn melasma and post-inflammatory pigmentation.
Read the breakdownResearch suggests wrinkle reduction
Brightens skin
Strengthens barrier
Research suggests may help with severe acne
Smooths fine lines and wrinkles
Broad-spectrum UV protection
Faster visible results than retinol
Broad-spectrum filter
Repairs barrier
Broad-spectrum
Strong acne efficacy
Supports clearer skin
Unclogs pores
Hydrates
UVA1 protection
Most potent topical retinoid
Targets stubborn melasma
Deep hydration
Reinforces barrier
Universal hydrator
Best-in-class occlusion
Barrier integrity
Stabilises antioxidants
UVA protection
Reduces inflammatory acne and rosacea
Strongest cica form
Deep dermal penetration
Reduces fine lines
Smooths skin
Soothes redness
Retinol-like anti-aging without irritation
Resurfaces skin
Restores barrier
UVB protection
Broad-spectrum
UV protection
Stimulates hair growth
Effective for hormonal acne
Boosts collagen
Strengthens barrier
Restores barrier
Lipid-phase antioxidant
Strongest depigmenting agent
Fades dark spots
Soothes
Kills acne bacteria
Retinoid efficacy without retinisation
Gentle exfoliation
Soothes itch
Stimulates collagen and elastin
Sebum-balancing
Stronger wound healing than whole extract
Protects against pollution
Controls sebum
Improves clarity
Restores barrier
Stable
Ultra-gentle exfoliation
Dual humectant and keratolytic
Deep hydration
Antioxidant
Brightens
Gentle resurfacing
Smooths wrinkles
Holds more water than HA
Brightens
Restores barrier
Strengthens barrier
Ceramide precursor
Anti-aging
Collagen stimulation
Brightens
Antifungal scalp treatment
Internal/external photoprotection
Dual-release retinoid action
Stable across pH
Brightens
Hydrates as it exfoliates
Boosts collagen
Hydrates
Deep emollience
Cohesive barrier
Strongest natural antioxidant
Strongest mitochondrial antioxidant
Anti-inflammatory
DNA repair support
Stable Vitamin C
Gentle resurfacing
Targets inflammaging
Higher water-binding than HA
Restores barrier
Smooth, silky feel
Strengthens barrier
Universal antioxidant network booster
Selective tissue antioxidant
Reduces inflammatory acne
Accelerates healing
Brightens
Reduces under-eye puffiness
Anti-glycation
Gentle BHA action
Antioxidant
Strong anti-inflammatory
Reduces dark spots
Biomimetic sebum analog
Stable Vitamin E
Reduces melasma
Antioxidant
Anti-acne
Anti-inflammatory acne treatment
Multi-pathway regeneration
Microbiome support
Antifungal
Replenishes NMF
Strong antioxidant
Anti-inflammatory
Gentle BHA alternative
Hydrates
Repairs barrier
Lightweight glow
Anti-inflammatory
Calms irritation
Calms redness
Stimulates fibroblasts
UVA protection
Lightweight glow
Brightens
Highest GLA content
Soothes
Reduces DHT effects on follicles
Antioxidant
Gentle multi-action brightening
Mid-strength exfoliation
Tightens jawline
Lightweight feel
Anti-inflammatory
Antimicrobial
Enzymatic antioxidant
Protects against UV-induced collagen breakdown
Soothes
Strong collagen stimulation
Anti-scarring
Gentle brightening
Softens expression lines
Reduces expression lines
Hydrates
Cost-effective barrier repair
Brightens
Gentle BHA action
Restores NMF
Brightens
Restores barrier
Brightens
Reduces expression lines
Antibacterial
Restores barrier
Reduces expression lines
Hydrates
Hydrates
Sebum-mimetic
Restores barrier FFA component
Hydrating film-former
Strong anti-inflammatory
Antibacterial
Anti-apoptotic
UVB protection
Stable
Longevity pathway activation
Hydrates
Gentle brightening
Light occlusion
Antioxidant
Antibacterial
UVB protection
Natural silicone alternative
Reduces bruising
Soothes
Hydrating
Ultra-gentle introduction to retinoids
Gentle brightening
Buffers AHA blends
Light, dry feel
Softens skin
Hydrating
UVB protection
Supports keratinocyte differentiation
Concentrated antioxidants
Surface hydration
UVB protection
Mild hydration
Deep occlusion
Astringent
pH adjustment
Hydrates
Stimulates fibroblast activity
Quick-drying
Marketing-driven anti-aging
Supports keratin synthesis
Vasodilator