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Sodium Hyaluronate

INCI: Sodium Hyaluronate
Also known as: HA salt, Low-MW Hyaluronate
HydrationhumectantbiotechStrong evidencePregnancy safe
89
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
0.1%–2%
How It Works

The sodium salt of hyaluronic acid. Smaller molecular weight allows deeper penetration into the upper epidermis.

Lower-MW polymer penetrates beyond the stratum corneum, increasing dermal water binding more efficiently than parent HA.

pH Range
5.0–8.0
Benefits
  • Deep hydration
  • Lightweight feel
  • Plumps
  • Soothes
  • Pairs with all actives
Proven For

What the evidence supports.

DehydrationFine linesTight skin
Best For
  • All skin types
Avoid If

No notable contraindications reported.

Layering Order
4/10

Mid-routine serum or treatment step.

Max Safe Concentration
2%

Concentration range in well-formulated products: 0.1%–2%

Seasonal Use

Year-round.

Nutrition Connection

Same as HA.

Skin Signals When You Need It
  • Surface dehydration
For Estheticians & Professionals

Multi-weight blends (5kDa + 50kDa + 1MDa) deliver layered hydration across skin depths.

Clinical Evidence

The research behind Sodium Hyaluronate.

4 peer-reviewed studies

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Randomized Controlled Trial
Nano-hyaluronic acid significantly improved skin hydration and elasticity after 8 weeks.
Jegasothy SM, Zabolotniaia V, Bielfeldt S
Journal of Clinical and Aesthetic Dermatology, 2014
View Study →
Systematic Review
Oral collagen peptides at 2.5-10g daily significantly improved skin elasticity and reduced wrinkle depth after 8-12 weeks across 11 RCTs.
Choi FD, Sung CT, Juhasz MLW, Mesinkovska NA
Journal of Drugs in Dermatology, 2019
View Study →
Systematic Review
Estrogen deficiency following menopause causes 30% reduction in skin collagen within the first 5 years.
Wilkinson HN, Hardman MJ
Maturitas, 2017
View Study →
Systematic Review
Chronic psychological stress elevates cortisol, accelerating skin aging through collagen degradation and barrier disruption.
Chen Y, Lyga J
Inflammation and Allergy Drug Targets, 2014
View Study →
Pairs Well With
NiacinamidePeptides (Matrixyl)GlycerinCeramide NP
Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility

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