Ceramide AP

INCI: Ceramide AP
Also known as: Ceramide 6 II
BarrierbarrierbiotechStrong evidencePregnancy safe
89
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
0.1%–1%
How It Works

An α-hydroxy ceramide critical to barrier hydration in mature skin, where its native levels decline most steeply.

Forms hydrogen-bonded lamellar structures with cholesterol and free fatty acids, restoring the mortar between corneocytes.

pH Range
4.0–7.0
Benefits
  • Reinforces barrier
  • Plumps mature skin
  • Reduces sensitivity
Proven For

What the evidence supports.

Mature skinEczemaAtopic dermatitis
Best For
  • Mature
  • Dry
  • Sensitive
Avoid If

No notable contraindications reported.

Layering Order
7/10

Later treatment or moisturiser step.

Max Safe Concentration
1%

Concentration range in well-formulated products: 0.1%–1%

Seasonal Use

Year-round.

Nutrition Connection

Same as Ceramide NP.

Skin Signals When You Need It
  • Mature-skin TEWL
For Estheticians & Professionals

Often blended with NP and EOP for full-spectrum barrier repair.

Clinical Evidence

The research behind Ceramide AP.

1 peer-reviewed study

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Systematic Review
Vitamin D deficiency significantly associated with acne vulgaris, atopic dermatitis and psoriasis.
Mostafa WZ, Hegazy RA
Journal of Advanced Research, 2015
View Study →
Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility

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