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Ceramide EOP

INCI: Ceramide EOP
Also known as: Ceramide 1
BarrierbarrierbiotechStrong evidencePregnancy safe
88
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
0.05%–0.5%
How It Works

An esterified ceramide that anchors the lipid matrix to corneocytes. Essential for the integrity of mature, eczema-prone skin.

Provides the long-chain linker between adjacent lipid bilayers, locking the barrier scaffold into a continuous sheet.

pH Range
4.0–7.0
Benefits
  • Barrier integrity
  • Moisturisation
  • Anti-inflammatory
Proven For

What the evidence supports.

EczemaAtopic dermatitisSensitivity
Best For
  • Dry
  • Mature
  • Atopic
Avoid If

No notable contraindications reported.

Layering Order
7/10

Later treatment or moisturiser step.

Max Safe Concentration
0.5%

Concentration range in well-formulated products: 0.05%–0.5%

Seasonal Use

Year-round.

Nutrition Connection

Same as Ceramide NP.

Skin Signals When You Need It
  • Recurrent eczema flares
For Estheticians & Professionals

Required in evidence-based eczema moisturisers (e.g. EpiCeram).

Clinical Evidence

The research behind Ceramide EOP.

3 peer-reviewed studies

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Systematic Review
Vitamin D deficiency significantly associated with acne vulgaris, atopic dermatitis and psoriasis.
Mostafa WZ, Hegazy RA
Journal of Advanced Research, 2015
View Study →
Systematic Review
Chronic psychological stress elevates cortisol, accelerating skin aging through collagen degradation and barrier disruption.
Chen Y, Lyga J
Inflammation and Allergy Drug Targets, 2014
View Study →
Randomized Controlled Trial
Ceramide-dominant emollients improved skin barrier function by 63% within 6 weeks.
Draelos ZD, Ertel K, Berge C
Cutis, 2006
View Study →
Pairs Well With
Ceramide NPCeramide APCholesterolFree fatty acids
Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility

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