Amino Acid Complex

INCI: Amino Acid Blend

Also known as: NMF amino acids

HydrationhumectantsyntheticModerate evidencePregnancy safe

Skinlumis Rating

Comedogenic

0/5

Irritancy

0/5

Best applied

Both

Effective range

1%–10%

How It Works

A blend of glycine, alanine, serine, proline, etc., the building blocks of skin's natural moisturising factor.

Provides the amino acid component of NMF, binding water in the stratum corneum and supporting keratin synthesis.

pH Range

4.0–7.0

Benefits

Replenishes NMF
Hydrates
Supports keratin
Soothes

Proven For

What the evidence supports.

DehydrationNMF depletionSensitive skin

Best For

All skin types

Avoid If

No notable contraindications reported.

Layering Order

4/10

Mid-routine serum or treatment step.

Max Safe Concentration

10%

Concentration range in well-formulated products: 1%–10%

Seasonal Use

Year-round.

Nutrition Connection

Dietary protein supplies skin amino acid pools.

Skin Signals When You Need It

Tight, dull, dehydrated skin

For Estheticians & Professionals

Synergistic with HA + Sodium PCA in 'NMF mimetic' formulas.

Clinical Evidence

The research behind Amino Acid Complex.

1 peer-reviewed study

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Randomized Controlled Trial

Nano-hyaluronic acid significantly improved skin hydration and elasticity after 8 weeks.

Jegasothy SM, Zabolotniaia V, Bielfeldt S
Journal of Clinical and Aesthetic Dermatology, 2014

View Study →

Pairs Well With

Hyaluronic Acid Sodium PCA Ceramide NP

Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility