Ceramide EOS

INCI: Ceramide EOS

Also known as: Ceramide 4

BarrierbarrierbiotechModerate evidencePregnancy safe

Skinlumis Rating

Comedogenic

0/5

Irritancy

0/5

Best applied

Both

Effective range

0.05%–0.3%

How It Works

An esterified ω-hydroxy ceramide that links corneocytes covalently. Crucial for cohesion of the cornified envelope.

Long-chain ester crosslinks corneocyte lipid envelopes, stabilising the entire stratum corneum architecture.

pH Range

4.0–7.0

Benefits

Cohesive barrier
Reduces sensitivity

Proven For

What the evidence supports.

EczemaAtopic skin

Best For

All skin types

Avoid If

No notable contraindications reported.

Layering Order

7/10

Later treatment or moisturiser step.

Max Safe Concentration

0.3%

Concentration range in well-formulated products: 0.05%–0.3%

Seasonal Use

Year-round.

For Estheticians & Professionals

Often included in eczema-targeted cosmeceuticals.

Clinical Evidence

The research behind Ceramide EOS.

1 peer-reviewed study

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Systematic Review

Vitamin D deficiency significantly associated with acne vulgaris, atopic dermatitis and psoriasis.

Mostafa WZ, Hegazy RA
Journal of Advanced Research, 2015

View Study →

Pairs Well With

Ceramide NP Ceramide EOP

Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility