Ceramide NG
INCI: Ceramide NG
Also known as: Ceramide 2 variant
BarrierbarrierbiotechModerate evidencePregnancy safe
78
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
0.05%–0.5%
How It Works
A skin-identical non-hydroxy ceramide used in dermatologic barrier formulations.
Integrates into lamellar lipid matrix supporting barrier function.
pH Range
4.0–7.0
Benefits
- Strengthens barrier
- Hydrates
Proven For
What the evidence supports.
Barrier weakness
Best For
- All skin types
Avoid If
No notable contraindications reported.
Layering Order
7/10
Later treatment or moisturiser step.
Max Safe Concentration
0.5%
Concentration range in well-formulated products: 0.05%–0.5%
Seasonal Use
Year-round.
For Estheticians & Professionals
Less common solo, appears in proprietary blends.
Clinical Evidence
The research behind Ceramide NG.
Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.
Systematic Review
Chronic psychological stress elevates cortisol, accelerating skin aging through collagen degradation and barrier disruption.
Chen Y, Lyga J
Inflammation and Allergy Drug Targets, 2014
View Study →Inflammation and Allergy Drug Targets, 2014
Randomized Controlled Trial
Ceramide-dominant emollients improved skin barrier function by 63% within 6 weeks.
Draelos ZD, Ertel K, Berge C
Cutis, 2006
View Study →Cutis, 2006
Pairs Well With
Conflicts With
No flagged conflicts. Still, patch-test new actives.
Your Skin Compatibility
Sign up to see how Ceramide NG fits your skin archetype and personalised protocol.