Sulfur

INCI: Sulfur
Also known as: Precipitated sulfur
AcneactivemineralModerate evidencePregnancy safe
70
Skinlumis Rating
Comedogenic
0/5
Irritancy
3/5
Best applied
Both
Effective range
3%–10%
How It Works

An old-school keratolytic and antimicrobial used for acne, rosacea, and seborrheic dermatitis. Distinctive sulfur odour.

Converts to pentathionic acid on skin, killing C. acnes; mild keratolytic action; reduces sebum.

pH Range
3.0–7.0
Benefits
  • Antibacterial
  • Anti-fungal
  • Sebum control
  • Useful for rosacea papules
Proven For

What the evidence supports.

AcneRosaceaSeborrheic dermatitis
Best For
  • All skin types
Avoid If
  • Sulfa allergy (caution)
  • Very dry skin
Layering Order
5/10

Mid-routine serum or treatment step.

Max Safe Concentration
10%

Concentration range in well-formulated products: 3%–10%

Seasonal Use

Year-round.

Nutrition Connection

Dietary sulfur from cruciferous vegetables, alliums, eggs.

Skin Signals When You Need It

No specific deficiency signals tracked for this ingredient.

For Estheticians & Professionals

10% masks are great spot-treatment; nightly use can dry sensitive skin.

Clinical Evidence

The research behind Sulfur.

4 peer-reviewed studies

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Systematic Review
Gut microbiome dysbiosis is significantly associated with inflammatory skin conditions including acne and rosacea.
Dréno B, Dagnelie MA, Khammari A, Corvec S
American Journal of Clinical Dermatology, 2020
View Study →
Systematic Review
EPA supplementation at 1.8g/day reduced inflammatory acne lesions by 42% over 12 weeks.
Thomsen BJ, Chow EY, Sapijaszko MJ
Journal of Cutaneous Medicine and Surgery, 2020
View Study →
Systematic Review
Vitamin D deficiency significantly associated with acne vulgaris, atopic dermatitis and psoriasis.
Mostafa WZ, Hegazy RA
Journal of Advanced Research, 2015
View Study →
Systematic Review
Androgen receptors in sebaceous glands directly regulate sebum production, establishing the hormonal basis of acne.
Makrantonaki E, Ganceviciene R, Zouboulis C
Dermato-Endocrinology, 2011
View Study →
Pairs Well With
Sodium SulfacetamideSalicylic Acid
Conflicts With

No flagged conflicts. Still, patch-test new actives.

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