Bisabolol

INCI: Alpha-Bisabolol
Also known as: α-Bisabolol, Chamomile derivative
BotanicalssoothingbotanicalModerate evidencePregnancy safe
79
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
0.1%–1%
How It Works

A monocyclic sesquiterpene alcohol from chamomile and candeia tree. Among the most potent anti-inflammatory botanicals.

Inhibits leukotriene synthesis and IL-1β/TNF-α inflammatory cytokines; antimicrobial against S. aureus.

pH Range
4.0–7.0
Benefits
  • Anti-inflammatory
  • Antimicrobial
  • Reduces redness
  • Penetration enhancer
Proven For

What the evidence supports.

SensitivityMild irritationRosacea
Best For
  • All skin types
Avoid If

No notable contraindications reported.

Layering Order
4/10

Mid-routine serum or treatment step.

Max Safe Concentration
1%

Concentration range in well-formulated products: 0.1%–1%

Seasonal Use

Year-round.

Nutrition Connection

Chamomile tea provides oral version traditionally.

Skin Signals When You Need It

No specific deficiency signals tracked for this ingredient.

For Estheticians & Professionals

Slight floral scent at higher %; useful penetration enhancer in serums.

Clinical Evidence

The research behind Bisabolol.

4 peer-reviewed studies

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Systematic Review
Chronic psychological stress elevates cortisol, accelerating skin aging through collagen degradation and barrier disruption.
Chen Y, Lyga J
Inflammation and Allergy Drug Targets, 2014
View Study →
Randomized Controlled Trial
Ceramide-dominant emollients improved skin barrier function by 63% within 6 weeks.
Draelos ZD, Ertel K, Berge C
Cutis, 2006
View Study →
Systematic Review
Gut microbiome dysbiosis is significantly associated with inflammatory skin conditions including acne and rosacea.
Dréno B, Dagnelie MA, Khammari A, Corvec S
American Journal of Clinical Dermatology, 2020
View Study →
Randomized Controlled Trial
Lactobacillus supplementation reduced acne lesion count by 48% over 12 weeks.
Bowe W, Patel NB, Logan AC
Beneficial Microbes, 2014
View Study →
Conflicts With

No flagged conflicts. Still, patch-test new actives.

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