Allantoin
A keratolytic and skin-softening agent that calms irritation and accelerates desquamation of damaged cells.
Increases cell proliferation, softens keratin (mild keratolysis), and forms complexes with irritants to neutralize them.
- Calms irritation
- Softens skin
- Supports recovery of minor wounds
- Universal tolerability
What the evidence supports.
- All skin types
No notable contraindications reported.
Mid-routine serum or treatment step.
Concentration range in well-formulated products: 0.1%–2%
Year-round.
Endogenous metabolite of uric acid.
No specific deficiency signals tracked for this ingredient.
Inexpensive workhorse soothing ingredient, included in most calming formulas.
The research behind Allantoin.
Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.
Inflammation and Allergy Drug Targets, 2014
Cutis, 2006
No flagged conflicts. Still, patch-test new actives.
Sign up to see how Allantoin fits your skin archetype and personalised protocol.
2 studies from the Intelligence Vault that discuss Allantoin.
- expert opinion · Int J Mol SciLiposomal Helix aspersa Snail Mucus: A Biomacromolecular Platform for Attenuating Chronological Skin Aging Through Modulation of miR-34a-Associated Senescence and Extracellular Matrix Remodeling.
- expert opinion · Biomol BiomedHidden benefits of snail mucus: A natural skincare marvel.