The plain-language read
Dear Editor, From a scientific perspective, snail mucus, or snail secretion filtrate (SSF), has emerged as a significant discovery in dermatology and regenerative medicine. Several studies on mucus composition have illuminated its features in recent years, yet much remains unexplored. High-quality snail mucus contains adequate levels of active substances (e.
- Biomol Biomed. 2024 Aug 13;25(11):2578-2579. doi: 10.17305/bb.2024.11067.
- Hidden benefits of snail mucus: A natural skincare marvel.
Relevant if you're working with peptides, glycolic acid, allantoin for aging and dehydration.
What this means for your routine
If you're targeting aging, this research supports adding peptides to your AM/PM routine.
If you're targeting aging, this research supports adding glycolic_acid to your AM/PM routine.
Translated from this study's findings, not a personal prescription. Pair with your existing protocol and your practitioner's guidance.
Technical Summary, For Professional Reference
Clinical context
1. Biomol Biomed. 2024 Aug 13;25(11):2578-2579. doi: 10.17305/bb.2024.11067. Hidden benefits of snail mucus: A natural skincare marvel. Bazeer AB(1), Nagarajan P(1), Gayathiri E(2).
Full abstract→
1. Biomol Biomed. 2024 Aug 13;25(11):2578-2579. doi: 10.17305/bb.2024.11067. Hidden benefits of snail mucus: A natural skincare marvel. Bazeer AB(1), Nagarajan P(1), Gayathiri E(2). Author information: (1)Department of Medical Biotechnology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission's Research Foundation (Deemed to be University), Kirumampakkam, Puducherry, India. (2)Department of Plant Biology and Plant Biotechnology, Guru Nanak College (Autonomous), Chennai, India. Dear Editor, From a scientific perspective, snail mucus, or snail secretion filtrate (SSF), has emerged as a significant discovery in dermatology and regenerative medicine. Several studies on mucus composition have illuminated its features in recent years, yet much remains unexplored. High-quality snail mucus contains adequate levels of active substances (e.g., allantoin, glycolic acid, proteins, glycosaminoglycans, and polyphenols). It comprises a complex mixture of proteins, enzymes, peptides, and trace minerals produced both externally and internally, which improves skin hydration, flexibility, and smoothness. This makes it an ideal ingredient for anti-aging creams, moisturizers, and serums. The beauty and pharmaceutical industries popularize commercial SSF products due to their natural composition and scientifically proven performance as a promising dermatological treatment. These products offer synergistic therapeutic effects, including cell signaling, tissue growth, tissue repair, wound healing, hydration, anti-aging properties, and exfoliation. Read more in the PDF. DOI: 10.17305/bb.2024.11067 PMCID: PMC12452115 PMID: 39145612 [Indexed for MEDLINE] Conflict of interest statement: Conflicts of interest: Authors declare no conflicts of interest.
Original source →Does Astragalus mongholicus Bunge help promote the healing of wounds? A systematic review and meta-analysis of preclinical animal studies.
Wounds continue to represent a significant public health challenge globally. In recent years, Astragalus mongholicus Bunge, a traditional Chinese botanical drug utilized for wound treatment, has garnered increasing research attention. However, the therapeutic efficacy and safety of this natural botanical drug on wound healing remain poorly understood.
Safety and efficacy of individualised exercise and NAD(+) precursor supplementation in patients with Friedreich's ataxia in the USA: a single-centre, 2 × 2 factorial, randomised controlled trial.
Friedreich's ataxia is a rare, chronic, progressive, neurodegenerative condition affecting multiple organ systems, including neurological, musculoskeletal, cardiac, and endocrine systems, and is marked by low cardiopulmonary fitness. We tested the effect of exercise and NAD+ precursor supplementation with nicotinamide riboside, which have each shown benefits in animal and early clinical studies, on cardiopulmonary fitness in individuals with Friedreich's ataxia. This 12-week, outpatient, phase 2, single-site (Children's Hospital of Philadelphia, Philadelphia, PA, USA), randomised, 2 × 2 factorial clinical trial recruited individuals aged 10-40 years with an ejection fraction of 45% or greater who were able to exercise.
Evaluation of Nicotinamide Riboside in Prevention of Small Nerve Fiber Axon Degeneration and Promotion of Nerve Regeneration.
Recent preclinical studies have shown that nicotinamide adenine dinucleotide (NAD+) plays a critical role in molecular mechanisms of axon degeneration, and reductions in NAD+ levels are associated with axonal degeneration. Nicotinamide riboside (NR) is a safe and widely available pyridine-nucleoside form of vitamin B3 and is an NAD+ precursor. To investigate if oral supplementation of synthetic NR can act as a therapeutic agent to prevent degeneration of small somatic sensory axons innervating the skin or promote regeneration of these same fibers in humans, we utilized a validated experimental model of cutaneous nerve degeneration and regeneration and conducted a placebo-controlled, double-blinded Phase 2 study.