Bee Venom

INCI: Bee Venom

Also known as: Apitoxin

AdvancedactivebotanicalAnecdotal evidenceNot for pregnancy

Skinlumis Rating

Comedogenic

0/5

Irritancy

3/5

Best applied

Effective range

0.0001%–0.01%

How It Works

A complex venom containing melittin, touted as a 'natural Botox' through transient micro-inflammation that boosts fibroblast activity.

Melittin causes transient micro-inflammation triggering fibroblast wound-healing response; mast cell degranulation can be problematic for allergic individuals.

pH Range

5.0–7.0

Benefits

Stimulates fibroblast activity
Marketed as Botox alternative

Proven For

What the evidence supports.

Mild rhytides

Best For

All skin types

Avoid If

Bee venom allergy
Atopic skin
Pregnant

Layering Order

5/10

Mid-routine serum or treatment step.

Max Safe Concentration

0.01%

Concentration range in well-formulated products: 0.0001%–0.01%

Seasonal Use

Year-round.

For Estheticians & Professionals

Always patch test; risk of severe allergic reaction in bee-sensitive individuals.

Pairs Well With

Hyaluronic Acid

Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility