Saccharomyces Ferment Filtrate

INCI: Galactomyces / Saccharomyces Ferment Filtrate

Also known as: Pitera (SK-II)

AdvancedactivebiotechModerate evidencePregnancy safe

Skinlumis Rating

Comedogenic

0/5

Irritancy

0/5

Best applied

Both

Effective range

5%–90%

How It Works

A yeast-fermentation extract famously used as 'Pitera' by SK-II. Rich in amino acids, organic acids, vitamins, and minerals.

Provides a complex of small-molecule nutrients including pyrroloquinoline quinone and B-vitamins that support keratinocyte energy metabolism.

pH Range

4.0–6.0

Benefits

Improves clarity
Smooths texture
Hydrates
Strengthens barrier

Proven For

What the evidence supports.

DullnessTextureMature skin

Best For

All skin types

Avoid If

No notable contraindications reported.

Layering Order

2/10

Apply early in routine, toner/essence step.

Max Safe Concentration

95%

Concentration range in well-formulated products: 5%–90%

Seasonal Use

Year-round.

Nutrition Connection

Fermented food cultures provide similar compounds dietarily.

Skin Signals When You Need It

Dull, uneven tone

For Estheticians & Professionals

Distinctive yeasty scent at high %; tolerance builds quickly.

Clinical Evidence

The research behind Saccharomyces Ferment Filtrate.

4 peer-reviewed studies

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Systematic Review

Oral collagen peptides at 2.5-10g daily significantly improved skin elasticity and reduced wrinkle depth after 8-12 weeks across 11 RCTs.

Choi FD, Sung CT, Juhasz MLW, Mesinkovska NA
Journal of Drugs in Dermatology, 2019

View Study →

Systematic Review

Estrogen deficiency following menopause causes 30% reduction in skin collagen within the first 5 years.

Wilkinson HN, Hardman MJ
Maturitas, 2017

View Study →

Systematic Review

Chronic psychological stress elevates cortisol, accelerating skin aging through collagen degradation and barrier disruption.

Chen Y, Lyga J
Inflammation and Allergy Drug Targets, 2014

View Study →

Randomized Controlled Trial

Nano-hyaluronic acid significantly improved skin hydration and elasticity after 8 weeks.

Jegasothy SM, Zabolotniaia V, Bielfeldt S
Journal of Clinical and Aesthetic Dermatology, 2014

View Study →

Pairs Well With

Niacinamide Hyaluronic Acid

Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility