Phytosphingosine
A precursor to ceramides synthesised by skin from sphingosine. Has additional antimicrobial action against acne-causing bacteria.
Converts in vivo to ceramides while exerting direct antimicrobial action against C. acnes and S. aureus.
- Ceramide precursor
- Antibacterial
- Anti-inflammatory
- Suitable for acne-prone barrier
What the evidence supports.
- All skin types
No notable contraindications reported.
Later treatment or moisturiser step.
Concentration range in well-formulated products: 0.1%–1%
Year-round.
Derived from yeast fermentation.
No specific deficiency signals tracked for this ingredient.
Hybrid barrier + antimicrobial, unique value for acne-prone clients with compromised barrier.
The research behind Phytosphingosine.
Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.
American Journal of Clinical Dermatology, 2020
Journal of Cutaneous Medicine and Surgery, 2020
Journal of Advanced Research, 2015
Dermato-Endocrinology, 2011
No flagged conflicts. Still, patch-test new actives.
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