Licorice Root Extract

INCI: Glycyrrhiza Glabra Root Extract
Also known as: Glycyrrhiza, Liquiritin, Glabridin
BrighteningbrighteningbotanicalModerate evidencePregnancy safe
79
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
1%–5%
How It Works

A botanical source of glabridin and liquiritin, natural tyrosinase inhibitors that also have steroid-like anti-inflammatory action.

Glabridin inhibits tyrosinase activity and UVB-induced pigmentation; liquiritin disperses existing melanin. Glycyrrhetinic acid provides cortisol-like anti-inflammatory effects.

pH Range
4.0–7.0
Benefits
  • Brightens
  • Soothes
  • Fades dark spots
  • Reduces redness
  • Multi-functional botanical
Proven For

What the evidence supports.

HyperpigmentationSensitivityRosacea
Best For
  • All skin types
  • Sensitive
Avoid If

No notable contraindications reported.

Layering Order
4/10

Mid-routine serum or treatment step.

Max Safe Concentration
5%

Concentration range in well-formulated products: 1%–5%

Seasonal Use

Year-round.

Nutrition Connection

Licorice root tea has been used in traditional medicine for centuries.

Skin Signals When You Need It

No specific deficiency signals tracked for this ingredient.

For Estheticians & Professionals

Excellent multi-tasker for sensitive pigmentation clients. Pairs especially well with centella for rosacea + PIH overlap.

Notable Research
  • Yokota et al. 1998, glabridin inhibited tyrosinase in vitro and reduced UVB pigmentation
Clinical Evidence

The research behind Licorice Root Extract.

4 peer-reviewed studies

Every claim on this page traces to published research. Findings below are drawn from randomized trials and systematic reviews, each links to the study on PubMed.

Randomized Controlled Trial
Vitamin C showed comparable efficacy to hydroquinone for melasma treatment.
Espinal-Perez LE, Moncada B, Castanedo-Cazares JP
International Journal of Dermatology, 2004
View Study →
Randomized Controlled Trial
Niacinamide inhibits melanosome transfer to keratinocytes, reducing hyperpigmentation by up to 35%.
Hakozaki T, Minwalla L, Zhuang J et al.
British Journal of Dermatology, 2002
View Study →
Randomized Controlled Trial
Azelaic acid comparable to hydroquinone for hyperpigmentation with superior safety across all Fitzpatrick types.
Balina LM, Graupe K
International Journal of Dermatology, 1991
View Study →
Systematic Review
Chronic psychological stress elevates cortisol, accelerating skin aging through collagen degradation and barrier disruption.
Chen Y, Lyga J
Inflammation and Allergy Drug Targets, 2014
View Study →
Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility

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