Madecassoside
INCI: Madecassoside
Also known as: Centella triterpene
BotanicalssoothingbotanicalModerate evidencePregnancy safe
82
Skinlumis Rating
Comedogenic
0/5
Irritancy
0/5
Best applied
Both
Effective range
0.1%–1%
How It Works
An isolated triterpene from Centella asiatica with the strongest wound-healing evidence in the genus.
Up-regulates TGF-β signalling for collagen-III synthesis; suppresses TNF-α and IL-6 inflammation.
pH Range
5.0–7.0
Benefits
- Stronger wound healing than whole extract
- Anti-inflammatory
- Targets post-procedure recovery
Proven For
What the evidence supports.
Post-procedureWound healingSensitive skin
Best For
- All skin types
Avoid If
No notable contraindications reported.
Layering Order
4/10
Mid-routine serum or treatment step.
Max Safe Concentration
1%
Concentration range in well-formulated products: 0.1%–1%
Seasonal Use
Year-round.
For Estheticians & Professionals
Star ingredient in luxury 'cica' lines.
Pairs Well With
Conflicts With
No flagged conflicts. Still, patch-test new actives.
Your Skin Compatibility
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