Urea

INCI: Urea

Also known as: Carbamide

HydrationhumectantsyntheticStrong evidencePregnancy safe

Skinlumis Rating

Comedogenic

0/5

Irritancy

1/5

Best applied

Both

Effective range

2%–10% (face) / 10%–40% (body)

How It Works

A natural NMF component with dual humectant + keratolytic action. At low % hydrates; at high % (10%+) it softens hyperkeratotic skin.

At <10% binds water in the stratum corneum; at higher % disrupts keratin structure, exfoliating thickened skin (heels, KP).

pH Range

5.0–8.0

Benefits

Proven For

What the evidence supports.

Keratosis pilarisCracked heelsXerosis

Best For

Avoid If

No notable contraindications reported.

Layering Order

4/10

Mid-routine serum or treatment step.

Max Safe Concentration

40% body

Concentration range in well-formulated products: 2%–10% (face) / 10%–40% (body)

Seasonal Use

Year-round; raise body % in winter.

Nutrition Connection

End product of protein metabolism.

Skin Signals When You Need It

For Estheticians & Professionals

10% body urea is a near-miracle for KP and rough elbows. Avoid open eczema cuts.

Pairs Well With

Conflicts With

No flagged conflicts. Still, patch-test new actives.

Your Skin Compatibility

The science behind Urea

3 studies from the Intelligence Vault that discuss Urea.