UBPJO exhibited significantly greater inhibitory effects compared to PJO against S.
Relevant if you're working with tocopherol, urea, pha for aging.
If you're targeting aging, this research supports adding tocopherol to your AM/PM routine. Effective concentration range: 5% based on this study.
If you're targeting aging, this research supports adding urea to your AM/PM routine. Effective concentration range: 5% based on this study.
Translated from this study's findings, not a personal prescription. Pair with your existing protocol and your practitioner's guidance.
1. Molecules. 2026 Apr 17;31(8):1324. doi: 10.3390/molecules31081324. Antioxidant, Photoprotective, and Antimicrobial Potential of Oil Extract of Usnea barbata L. F.H.Wigg from Călimani Mountains, Romania.
1. Molecules. 2026 Apr 17;31(8):1324. doi: 10.3390/molecules31081324. Antioxidant, Photoprotective, and Antimicrobial Potential of Oil Extract of Usnea barbata L. F.H.Wigg from Călimani Mountains, Romania. Dan MA(1), Nedea MI(1), Ozon EA(1), Ungurianu A(1), Ungureanu AR(2), Popovici V(3), Musuc AM(4), Bratan V(4), Cazacincu RG(5), Arsene AL(1), Lupuliasa D(1), Margina D(1). Author information: (1)Faculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 020945 Bucharest, Romania. (2)Department of Pharmacy, Sanador Clinical Hospital, 010991 Bucharest, Romania. (3)Center for Mountain Economics, "Costin C. Kiritescu" National Institute of Economic Research (INCE-CEMONT), Romanian Academy, 725700 Vatra-Dornei, Romania. (4)Institute of Physical Chemistry-Ilie Murgulescu, Romanian Academy, 060021 Bucharest, Romania. (5)Faculty of Pharmacy, Ovidius University of Constanta, 900470 Constanta, Romania. In order to enhance the value and stability of vegetable oils, they may be enriched with essential oils and plant extracts with strong antioxidant activity, yielding innovative formulations with potential applications in skincare. The present research aims to investigate the bioactive properties of an Usnea barbata extract in Jojoba oil (JO) enriched with 5% Peppermint oil (PEO), and 10% vitamin E (PJO). The oil extract (UBPJO) was obtained through cold maceration. The UBPJO antioxidant activity was investigated using ABTS (2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid)) and DPPH (2,2-diphenyl-1-picrylhydrazyl)-based methods. The sunscreen capacity of UBPJO was evaluated by measuring their sun protection factor (SPF) values. The antimicrobial potential was investigated against S. aureus, E. coli, and C. albicans. The antioxidant activity of UBPJO was 1.5 times higher than that of PJO. Consequently, the sunscreen efficacy (assessed by SPF measurements) indicated satisfactory UVB protection abilities against S. aureus (UBPJO vs. PJO: 32.41 vs. 30.58). UBPJO exhibited significantly greater inhibitory effects compared to PJO against S. aureus (MIC = 18.75 ± 6.25 vs. 37.50 ± 0.00, p < 0.05). and C. albicans (9.62 ± 2.87 vs. 37.5 ± 12.5, p < 0.05). The bioactive properties investigated in the present study support the inclusion of UBPJO in various skin protective formulations with antiaging, antibacterial, and antifungal effects. DOI: 10.3390/molecules31081324 PMCID: PMC13118391 PMID: 42076002 [Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest.
Original source →Wounds continue to represent a significant public health challenge globally. In recent years, Astragalus mongholicus Bunge, a traditional Chinese botanical drug utilized for wound treatment, has garnered increasing research attention. However, the therapeutic efficacy and safety of this natural botanical drug on wound healing remain poorly understood.
Recent preclinical studies have shown that nicotinamide adenine dinucleotide (NAD+) plays a critical role in molecular mechanisms of axon degeneration, and reductions in NAD+ levels are associated with axonal degeneration. Nicotinamide riboside (NR) is a safe and widely available pyridine-nucleoside form of vitamin B3 and is an NAD+ precursor. To investigate if oral supplementation of synthetic NR can act as a therapeutic agent to prevent degeneration of small somatic sensory axons innervating the skin or promote regeneration of these same fibers in humans, we utilized a validated experimental model of cutaneous nerve degeneration and regeneration and conducted a placebo-controlled, double-blinded Phase 2 study.
Nicotinamide (NAM) and Polypodium leucotomos extract (PL) have demonstrated photoprotective effects, but their role in preventing UVA-induced DNA damage in humans remains unclear. To evaluate the effects of oral NAM and PL on UVA-induced erythema and thymidine dimer (TT-dimer) formation. In this intraindividual trial, 50 healthy volunteers (phototypes I-III) were randomized (1:1) to receive either NAM (2000 mg daily) or PL (Heliocare Advanced: 480 mg daily) for 30 days.
This information is for educational purposes only and is not medical advice. Individual results vary. Consult a qualified dermatologist or healthcare professional for medical concerns. Full disclaimer →