Ovulatory phase: estrogen peak supports collagen synthesis and visible glow.
Cycle protocol: weeks 1–2 (follicular/ovulatory) — focus on hydration and brightening; weeks 3–4 (luteal/premenstrual) — add salicylic acid 1–2% and reduce comedogenic occlusives.
If you're targeting acne, this research supports adding salicylic acid to your AM/PM routine.
If you're targeting acne, this research supports adding niacinamide to your AM/PM routine.
Translated from this study's findings, not a personal prescription. Pair with your existing protocol and your practitioner's guidance.
Cycle-phase skin physiology: follicular phase characterized by low estradiol and decreased dermal hydration; ovulation peak estradiol drives collagen synthesis and visible luminosity; luteal progesterone elevation increases sebocyte activity and triggers premenstrual flare. Adjustable protocols outperform static regimens for cycling patients.
Skin physiology fluctuates predictably across the menstrual cycle. Follicular phase: low estrogen and progesterone produce drier, less elastic skin. Ovulatory phase: estrogen peak supports collagen synthesis and visible glow. Luteal phase: progesterone elevation increases sebum and triggers premenstrual acne. Cycle-aware skincare adjustments improve outcomes.
Original source →The combination of recombinant human epidermal growth factor (rhEGF) and fractional carbon dioxide (CO2) laser therapy is increasingly used in the treatment of facial atrophic acne scars. This study aimed to systematically assess the efficacy and safety of rhEGF combined with fractional CO2 laser therapy for managing facial atrophic acne scars. PubMed, Embase, the Cochrane Library, Web of Science, CNKI (China National Knowledge Infrastructure), Wanfang, SinoMed, and VIP were searched from inception to July 29, 2025.
L-Carnitine, an amino acid derivative critical for fatty acid metabolism, exhibits anti-inflammatory, antioxidant, and cytoprotective properties, with emerging applications in dermatology. This review explores its therapeutic potential, both topically and systemically, and its role as a biomarker in various skin disorders. A systematic search of Medline, EMBASE, and PubMed (1946-January 2025) was conducted, focusing on L-carnitine and dermatologic conditions, excluding acetyltransferases, acyltransferases, breast, and genetic metabolic diseases.
Bakuchiol (BAK), a meroterpene phenol abundant in the plant Psoralea corylifolia, is an emerging cosmeceutical agent with promising anti-aging, anti-inflammatory, and antibacterial properties. The trend for "clean" skincare products and search for anti-aging retinoid alternatives have poised BAK as a "must-have" ingredient in skincare. Our aim was to review the data for the applications of BAK in dermatology.
This information is for educational purposes only and is not medical advice. Individual results vary. Consult a qualified dermatologist or healthcare professional for medical concerns. Full disclaimer →